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ancient DNA

Ancient DNA is sequence information from the bones or tissues of organisms that come from historic or prehistoric collections. My work principally applies to prehistoric material, including skeletal material from Neandertals and Denisovans. Ancient DNA evidence on many kinds of organisms has become an important window into evolution.

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Chicken ancient DNA and artificial selection during medieval times

A study on change in European chickens over time illuminates the challenge of studying selection in populations with immigration from other sources.

Chicken ancient DNA and artificial selection during medieval times
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Research highlight: Use ancient remains more wisely

In this contribution, Keolu Fox and I consider what is necessary to build a sustainable science of ancient DNA.

Front page of "Use ancient remains more wisely"
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Geneticists work to understand how skeletons wound up in a mysterious Himalayan lake

Reviewing new work that reveals migrants from several historic periods in the skeletons surrounding this lake in India.

Roopkund Lake surrounded by snowy rocks
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How will ancient proteins change paleoanthropology?

Paleoproteomic methods may provide exciting avenues toward understanding pieces of fossils and their relationships.

Denisova 11 bone fragment in four views
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Should archaeologists really fear and loathe geneticists?

An article in Nature focuses on the tension between archaeologists and ancient DNA specialists.

Should archaeologists really fear and loathe geneticists?
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The so-called Toba bottleneck simply didn't happen

Prompted by a paper by Chad Yost and coworkers, I look at the persistent myth that humans were an endangered species only 74,000 years ago.

A volcanic eruption with ash cloud rising from caldera
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Secrets of the genome from Ust'-Ishim

A discovery from Siberia represents one of the earliest branches of modern humans to disperse into Eurasia.

Secrets of the genome from Ust'-Ishim
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New findings from the Denisova 3 genome at high coverage

Sequencing work by Matthias Meyer and coworkers highlights the demography of ancient Denisovans and genes that may make today's people different from them.

Sediment column in Denisova Cave showing labels with layer numbers
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What is the temporal bone from Darra-i-Kur, Afghanistan?

A bone from a historic excavation in Afghanistan raises the topic of genetic reanalysis of fragmentary fossils.

Temporal bone in four standard views