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introgression

Introgression is the incorporation of genes from one population into another population. Generally biologists use the term introgression when the populations are separated by substantial evolutionary distance, such as different species or lineages that have been separated by a long time.

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A hard ceiling on modern human dispersal

Neandertal DNA in some of the oldest modern human genomes establishes a short timeline of 50,000 years for the out-of-Africa founder event.

Silhouette cutout of Neandertal with trees and landscape visible through the cutout
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Tracing the signature of African-to-Neandertal gene flow

A new study of African genetic variation yields a more accurate picture of the genetic exchanges between ancient Africans and Neandertals 250,000 years ago.

DNA with chains of bubbles rising from it in a fluid
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Interaction and mixture: big picture and small

From the level of function of a single gene up to the movements of entire populations, our evolution was built from mixture.

Painting from 1883 of stone age dancers feasting around a fire
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When did human chromosome 2 fuse?

More and more, it looks like this event happened shortly before a million years ago, in the common ancestors of Neandertal, Denisovan, and African ancestral humans.

When did human chromosome 2 fuse?
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Climate models, Neandertals, and Denisovans

A new paper on biogeography of Neandertals and Denisovans raises ideas about the interactions of these groups.

A Neandertal-looking person dressed in animal skins lifting a stick and looking at a misty sunrise on snow.
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Tracing the genetic histories of ghost apes

The footprints of extinct lineages are the closest we have to a fossil record of the African apes.

Vivid brown eyes of a mountain gorilla
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Ghostbusters of human origins

Humans tend to mix and interact with each other. Geneticists are once again starting to take that seriously, changing their view of our origins.

Meme with the four movie Ghostbusters crossing the streams
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What color were Neandertals?

Even with whole genomes, scientists can't say very precisely what pattern of skin, hair, and eye pigmentation was in ancient populations like the Neandertals.

Fifteen Neandertal faces of varied ages and complexions
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Explaining the X chromosome hole in Neandertal ancestry

Natural selection reduced the variation on human X chromosomes in populations with the most Neandertal and Denisovan mixture. It may have been meiotic drive.

A fluorescence image of chromosomes in cells undergoing meiosis
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Fossil profile: Skhūl 1 and the mixing of populations

A child's skull from Mount Carmel gives an occasion to look at the history of ideas about population mixture.

Skhūl 1 calvaria with information
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Zlatý kůň and the Neandertal heritage of first Europeans

A skull from Czechia represents an individual from one of the earliest European modern human populations to encounter Neandertals.

Zlatý kůň cranium with information
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Ancient genetic introgression between cave hyenas and spotted hyenas

Describing the results of genomic work by Michael Westbury and collaborators, including ancient hyena genomes from Eurasia and North America.

Spotted hyena on a dark background
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Research highlight: Accurate depiction of uncertainty in ancient DNA research: The case of Neandertal ancestry in Africa

An article in the Journal of Social Archaeology looking at how researchers shaped public perceptions of Neandertal DNA heritage in living people.

Cover page of "Accurate depiction of uncertainty in ancient DNA research"
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Goat immunity modified by introgression during and after domestication

A new paper in Science Advances describes some of the evidence for selection on introgressed genes in goats.

Goat immunity modified by introgression during and after domestication
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Neandertals got 6% of their genomes from Africa

An analysis by Melissa Hubisz and coworkers finds that mtDNA is not all that Neandertals received from our African ancestors

A Banksy-style portrait of a Neandertal wearing a blazer
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How much Neandertal DNA do today's African peoples have?

New research shows that today's populations in Africa have around one third the Neandertal ancestry as people in Eurasia.

Neandertal face with hand holding a spear
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An enormous sample sheds light on the Denisovan ancestry of people in Iceland

Laurent Skov and coworkers have measured the very small amount of DNA shared within the Iceland population from Denisovan ancestry and they discuss several scenarios for how it may have gotten there.

An Iceland landscape with Northern Lights in the sky reflected in a lake
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Part of a Denisovan mtDNA resides in the nuclear genomes of many living people

A paper last week by Robert Bücking and coworkers trawled through the recently-sequenced Indonesian Genome Diversity Project dataset looking for snippets of mitochondrial DNA (mtDNA) that have been inserted into the nuclear genome. These snippets, called “NUMTs”, arise every so often as a result of DNA transfer from the mitochondrion

A reproduction of the Denisova 3 finger bone sits on a chalk outline of a hand
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Denisovan traits bring up the old problem of understanding morphological continuity

A paper by Shara Bailey and coworkers suggests that three-rooted lower molars are diagnostic of population mixture from Denisovans.

Fossil mandible from Xiahe, China, viewed from right side.
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How much sex did it take for Neandertal DNA to enter modern populations?

Addressing a widespread misconception about what geneticists are really measuring when they look at population mixture.

A painting of the biblical figures Jacob and Esau
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The Manot 1 skull and how we now look at Neandertal ancestry in early modern humans

The discovery of a 54,000-year-old skull in Israel sheds light on the dispersal of modern humans and their contacts with Neandertals.

Manot Cave with sloping sediment, archaeologists, and lights
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My reactions on the publication of the first draft Neandertal genome

Publication of the first draft of a Neandertal genome reveals that these ancient humans are among the ancestors of people living today.