A story by Susan Donaldson James of a unique genetic disorder and the social stigma of inbreeding in Appalachia: “Fugates of Kentucky: Skin Bluer than Lake Louise”.
By the time reports appeared in the media on the disorder, the Stacy family was upset with insinuations about in-breeding that fed into stereotypes of backwoods Appalachia.
"There was a pain not seen in lab tests," wrote Trost. "That was the pain of being blue in a world that is mostly shades of white to black."
The disorder involves an excess of methemoglobin in the blood, related to the examples I’ve been relating in my Anthropology 105 course the last week or so.