john hawks weblog

paleoanthropology, genetics and evolution

Without the code, it's hand-waving

Mon, 2012-09-03 23:03 -- John Hawks

A new post by C. Titus Brown is worth reading: "Anecdotal science"

I'm starting to notice that a lot of bioinformatics is anecdotal.

People publish software that "works for them." But it's not clear what "works" means -- all to often either the exact parameters or the specific evaluation procedure is not provided (and yes, there's a double standard here where experimental methods are considered more important than computational methods).

This means that their result is not an example of computational science. It's an anecdote.

He gives an example and discusses the real cost, which is that a published advance really doesn't advance anything, because everyone else has to spend so much time trying to get the code to work for their projects.

Time after time I'm reminded of my conversation with the big data astronomer, who reflected that his friends who are biologists complain that students are all being trained in computer programming instead of biology. Compared to astronomy, he said, biologists don't have a data problem at all.

Clearly, bioinformatics isn't taking seriously the need to really engineer software, with documentation and standard programming interfaces.

Neandertals

For years, I've worked on their bones. Now I'm working on their genes. Read more about the science studying these ancient people.

Denisova

From a finger bone of an ancient human came the record of a completely unexpected population. My lab is working on the science of the Denisova genome.

Acceleration

The advent of agriculture caused natural selection to speed up greatly in humans. We're uncovering some of the ways that populations have rapidly changed during the last 10,000 years.

Malapa

Just outside Johannesburg, the Malapa site is producing some of the most exciting finds in human evolution. This site is the headquarters of the Malapa Soft Tissue Project.