john hawks weblog

paleoanthropology, genetics and evolution

Impacts of gene mix-ups

Mon, 2010-06-07 09:17 -- John Hawks

Daniel MacArthur: "Sample swaps at 23andMe: a cautionary tale".

It appears that a single 96-well plate of customer DNA was affected by the mix-up. This resulted in incorrect results being sent to customers, with some alarming consequences; one mother posted on the 23andMe community about her distress upon discovering that her son's results were incompatible with the rest of the family:

Not a happy story of genetic discovery, but in the end her son is in fact her own. You hear about genetic information making people question their identity -- this is the depth of impact genetic testing can have.

It's also amazing to me that there are already families submitting swabs for both parents and children. Talk about disposable income!

Neandertals

For years, I've worked on their bones. Now I'm working on their genes. Read more about the science studying these ancient people.

Denisova

From a finger bone of an ancient human came the record of a completely unexpected population. My lab is working on the science of the Denisova genome.

Acceleration

The advent of agriculture caused natural selection to speed up greatly in humans. We're uncovering some of the ways that populations have rapidly changed during the last 10,000 years.

Malapa

Just outside Johannesburg, the Malapa site is producing some of the most exciting finds in human evolution. This site is the headquarters of the Malapa Soft Tissue Project.