All posts tagged with Neandertal DNA

Neandertal ancestors of African populations

5 minute read

Earlier this year, Lu Chen and coworkers from Joshua Akey’s research group published an assessment of the amount of Neandertal ancestry in the genomes of pre...

Neandertal sex acts are beyond counting

9 minute read

I’ve given a lot of thought over the years to the genetic ties between today’s people and ancient populations. Just last month, I wrote a lot about the relat...

Another Denisovan from Denisova Cave

10 minute read

Denisova Cave is one of the most fascinating places in the story of human origins. The cave is in the northern wall of the Anuy River valley, within the Alta...

Coming: ‘First Peoples’ on PBS

1 minute read

This month, PBS in the United States will be premiering a new five-part series on the origins and spread of modern humans around the world, called First Peop...

High recent admixture reported for Oase 1

1 minute read

Some readers have asked me what I think of the reporting from the recent Biology of Genomes conference, that Qiaomei Fu and colleagues from Svante Pääbo’s gr...

The genome from Ust’-Ishim

9 minute read

Qiaomei Fu and colleagues from Svante Pääbo’s lab have reported on a genome from northern Siberia that dates to 45,000 years ago. The genome comes from a hum...

A Neanderthal memoir

2 minute read

Carl Zimmer reviews Svante Paabo’s new book, Neanderthal Man: In Search of Lost Genomes, in the New York Times: “Missing Links”. Zimmer gives a balanced revi...

Ghost populations and ancient DNA

2 minute read

The rapidly changing field of ancient DNA has settled into a kind of normal science, as several teams of researchers have coalesced around a set of approache...

The Altai Neandertal

6 minute read

It is notable that we now have evidence for interbreeding among every kind of hominin we have DNA from, and some we don’t.

The Denisova-Sima de los Huesos connection

7 minute read

I direct your attention to a new paper by Mattias Meyer and colleagues describing a mitochondrial DNA sequence from Sima de los Huesos, Spain (Meyer et al. 2...

180 million Neandertals

less than 1 minute read

Just got back proofs of a book chapter I have coming out soon with Zach Throckmorton. My favorite paragraph:

A new high-coverage Neandertal genome

3 minute read

Today, Svante Pääbo’s group at the Max Planck Institute for Evolutionary Anthropology released high-coverage sequence data from a toe bone from Denisova Cave...

The Neandertal treatment

1 minute read

Virginia Hughes, in National Geographic News, takes on the subject of whether we will someday clone Neandertals: “Return of the Neanderthals”. She gets into ...

Speaking of Neandertal FOXP2

5 minute read

Tomislav Maricic and colleagues from Svante Pääbo’s group have reported finding a regulatory change in the gene FOXP2 that may be of relevance to the evoluti...

Send in the clones

1 minute read

I didn’t comment on the Neandertal cloning kerfuffle this week. Now that it’s sort of died down, I’ll provide a link to a Knight Science Journalism Tracker s...

Neandertal anti-defamation files, 17

2 minute read

Let no one say that I’m an uncritical voice about the many advantages of releasing preprints. They do have their downsides. Lack of editing is one.

"Decoding Neanderthals" to be broadcast

1 minute read

NOVA on American PBS stations has produced a new documentary about Neandertals: “Decoding Neanderthals”. They have just announced that it will be broadcast J...

ASHG notes on Gene Expression

2 minute read

Razib Khan has started writing up his notes on this week’s conference of the American Society of Human Genetics: “Reflections on the evolution at ASHG 2012”....

Neandertal piece

less than 1 minute read

A piece on my desktop that I’ve been meaning to blog is by Sarah Zielinsky in National Geographic News: “Neanderthals … They’re Just Like Us?”. Several good ...

The North African Neandertal descendants

4 minute read

A new paper by Federico Snchez-Quinto and colleagues reports on comparisons of North African population samples with the Neandertal DNA project data Sanchez-...

The fused chromosome 2 was in Denisova

1 minute read

In my post on the new Denisova paper the other day (“Denisova at high coverage”), I forgot to mention one interesting detail in the new paper by Mattias Meye...

Denisova at high coverage

10 minute read

Science today has released the new paper on the Denisova high-coverage genome by Mattias Meyer and colleagues from Svante Pääbo’s group Meyer:Denisova:2012. ...

Neandertal ancestry "Iced"

7 minute read

UPDATE (2015-10-21): This post has gotten some attention from social media recently, because Ötzi has been in the news. Later analyses have made clear that o...

Fusing chromosomes

2 minute read

Carl Zimmer recounts recent research by Evan Eichler’s group on the evolution of human chromosome 2, which represents a fusion of two separate chromosomes in...

How I got into anthropology

less than 1 minute read

I was noodling around online and found a video interview from last year’s Darwin Day event here at UW. Regular readers won’t learn anything new in the first ...

Quantum of solace

less than 1 minute read

I just want to point out, on the “six generations of daughters” story…

The Neandertal pigmentation race

1 minute read

As regular readers know, I’ve been detailing some of our work on the pigmentation genes of Neandertal and Denisova genomes. I got interrupted in the middle o...

Denisova APOE status

1 minute read

I got thinking this evening about APOE, which includes a very well-known polymorphism of three alleles, where the most ancient (ApoE4) is associated signific...

Over coffee

less than 1 minute read

G: Guess what Daddy and I learned last night? I'm more Neandertal than he is!

A quick look at your Neandertal fraction

1 minute read

The 23andMe blog, the Spittoon, has a description of their new technique to use 23andMe SNPs to estimate any customer’s fraction of Neandertal: “Find your in...

How widespread is Denisovan ancestry today?

6 minute read

Last month, David Reich and colleagues Reich:Denisova:2011 reported on estimates of Denisovan ancestry for island and mainland Asian populations. Their most ...

Archaic genome snooping from GWAS

2 minute read

The 23andMe blog reports on a recent genome-wide association study of type 2 diabetes in South Asian people: “SNPWatch: Genetic Variants Associated with Type...

No Neandertal safe sex

7 minute read

Laurent Excoffier and colleagues’ work has investigated how range expansions may have affected human genetic diversity. I’ve commented on this work several t...

Mailbag: mtDNA ancestor and speciation?

1 minute read

I've got a question about something I wrote in a newsgroup in 1995. Okay, that doesn't sound overly urgent, right? The general subject has come up again fo...

Mailbag: Where did Neandertals come from?

1 minute read

Dr. Hawks, I greatly enjoyed your course on the rise of humans I purchased through the Teaching Company. I could not find the answer to this question: ...

Ancient genomes review

2 minute read

Mark Stoneking and Johannes Krause present a review article in the current Nature Reviews Genetics Stoneking:Krause:2011 that gives an overview of the scienc...

Ancient genomes giving up their secrets

2 minute read

Last week, Nature ran a story by Ewen Callaway Callaway:Neandertal:2011 that hits the highlights of research on ancient genomes this year: “Ancient DNA revea...

Older and younger Acheulean in India

6 minute read

Shanti Pappu and colleagues Pappu:2011 report on date estimates resulting from new excavations at the old site of Attarampakkam, India. The news element is t...

Neandertal taste

2 minute read

I didn’t comment on this study when it came out in 2009, but as I’m reviewing some materials I thought it worth taking down a note. Carles Lalueza-Fox and co...

The real "junk" DNA

5 minute read

Let me be honest: when I started doing paleoanthropology, I really did not expect I’d be talking about Neandertal penises.

Neandertal segments of X chromosomes

15 minute read

Last year, this Neandertal genome came out. No doubt you’ve heard about it. So maybe by now you’re wondering where the new science is that’s being done on th...

Denisovans did not have red hair

6 minute read

At least, the Denisova sequence does not have any of the variants in humans that are associated with red hair. Nor does it share the unique Neandertal varian...

Denisova microcephalin status

4 minute read

I’m still doing quick mining of the Denisova sequence for obvious things. One of the simplest is the polymorphism in microcephalin (MCPH1) that Evans and col...

Denisova FOXP2 status

2 minute read

In the Denisova hubbub last month (“Denisova genome FAQ”) I didn’t hear anyone talking about the FOXP2 sequence of the Denisovans. I can’t swear that the pap...

Merry Christmas

less than 1 minute read

Razib’s post, “The paradigm is dead, long live the paradigm”, is a personal remembrance of the modern human origins problem, from his perspective. It include...

The Denisova genome FAQ

20 minute read

Today, a paper by David Reich and colleagues presents the nuclear genome of the Denisova pinky bone Reich:Denisova:2010. This is the second whole genome of a...

Neandertal band of brothers

5 minute read

Carles Lalueza-Fox and colleagues Lalueza-Fox:patrilocal:2010 have a new analysis of the mitochondrial DNA from El Sidrón, Spain. The site has a minimum numb...

Neandertal stories on parade

4 minute read

Long-time science journalist Robin McKie has a long article in The Observer about the Neandertals this weekend: “Neanderthals: how needles and skins gave us ...

Ozzy Osbourne, archaic human

1 minute read

Via a reader: The Daily Mail really aims for the lowest common denominator of genetics: “We’ve all suspected, now it’s official: Ozzy Osbourne IS a Neanderth...

Neandercomic

less than 1 minute read

A comic-page exposition of Neandertal DNA is online from Scientific American MIND.

Quote: Boyd on New World pigmentation clines

5 minute read

I’m using some statistics out of William Boyd’s 1956 printing of Genetics and the Races of ManBoyd:1956. It gives a good accounting of blood group data known...

Mailbag: Neandertal backbreeding

1 minute read

In your blog, you have commented on the prospect of re-creating a neandertal from a "completed" genome.....I agree with your views and predictions.

Migration thinking

1 minute read

Murray Cox and Michael Hammer have a short commentary piece in the current BMC Biology, titled, “A question of scale: Human migrations writ large and small” ...

Time to revise the mtDNA timescale?

5 minute read

Krzysztof Cyran and Marek Kimmel (2010) have presented a revised set of estimates of the human mtDNA most recent common ancestor (MRCA). It’s an interesting...

Adopt a Neandertal

1 minute read

Kyle Munkittrick of the “Science Not Fiction” blog argues, “Yes, we should clone Neanderthals.”

Mailbag: Neandertal-human branch lengths

1 minute read

In their recent paper (1, p.13) Prfer et al. are quite explicit about how they estimate the average divergence age for the human/Neanderthal lineages; assumi...

The Neandertal fraction

3 minute read

I’ve gotten the same question a few times, and have seen it elsewhere, so I thought it would be worth a short post to explain it. And for those readers who’v...

Population models and testing human origins

10 minute read

Earlier in the week, I pointed to a news story about upcoming research that substantiates some amount of gene flow among Pleistocene groups, persisting into ...

What kangaroos do…

2 minute read

In the current issue of Heredity, Neaves and colleagues describe the results of their analysis of 12 microsatellite loci and the mtDNA of two kangaroo specie...

More X-Woman thoughts

3 minute read

I had a great session with my advanced students yesterday running through different evolutionary scenarios for the X-Woman. This and some later posts will fo...

The Denisova mtDNA sequence: The X-Woman

9 minute read

In this week’s copy of Nature, Johannes Krause and colleagues Krause:Denisova:2010 report on the complete mitochondrial sequence of a pinky bone from Denisov...

An insertion into deep history

6 minute read

A couple of weeks ago I noted a new article by Chad Huff and colleagues in PNAS. It wasn’t available yet when I wrote, but I’ve had the chance to study it no...

The Human Spark, episode 1

6 minute read

I got to sit down and watch most of the first episode of “The Human Spark” on PBS tonight (my earlier post). Our local station shows these things later than ...

Methylation in Neandertals

4 minute read

A new Neandertal (and mammoth) genetics paper from Adrian Briggs and colleagues is bigger news than it might appear at first glance:

He ain't heavy

less than 1 minute read

It’s a teeny little story by Ewen Calloway at New Scientist, but they’ve given it the best headline:

The year's big paleoanthropology stories

1 minute read

Last year, I complained that paleoanthropology had been exceptionally boring. One piece of evidence was the year-end retrospective in Discover about the top ...

Neandertals talking from the past

less than 1 minute read

I’m getting a lot of hits this month on a post from last year, “The amazing talking Neandertals”. Don’t know why….

Pbo on Neandertal sequencing

1 minute read

On Edge, Svante Pääbo has a long and interesting narrative about Neandertal genetics, FoxP2 mice, his own biography, and everything else. Nothing new to be h...

Neandertals and bears

11 minute read

For most of their prehistory, humans were highly mobile hunter-gatherers. We can expect that Neandertals were also highly mobile, at least compared to sedent...

Neandertal races?

7 minute read

There’s a new paper in PLoS ONE by Virginie Fabre, Silvana Condemi and Anna Degioanni, titled “Genetic evidence of geographical groups among Neanderthals.” I...

The 10,000 Year Explosion

4 minute read

I want to point people interested in recent human evolution to a new book, The 10,000 Year Explosion: How Civilization Accelerated Human Evolution.

Neandertal: The Resurrection

4 minute read

Friday morning, I got back to teaching after my trip this week. So I filled my students in a bit about the Neandertal genome. One of them had been reading th...

An MAPT review

3 minute read

Elizabeth Pennisi writes this week a news focus in Science about the genome region labeled 17q21.31. I’m probably one of the few people who would recognize t...

Neandertal, other ancient DNA review

1 minute read

Last week, a short article in Science by Rachel Mackelprang and Edward Rubin discussed some of the recent advances in ancient DNA extraction. Of most interes...

Introgression encore

5 minute read

Although I've had a number of papers come out this year, there are two in particular that I've been working on for quite a long time. Both papers began thei...

The amazing talking Neandertals

15 minute read

This week, Johannes Krause and colleagues from the Max Planck Evolutionary Anthropology institute announced that they had tickled FoxP2 out of two Neanderta...

The PBS science showdown

2 minute read

I like my science-show narrators disembodied. I especially like it if they sound like Liev Schreiber. Alec Baldwin, I don't mind, although I always feel lik...

The inevitability of introgression

5 minute read

I'd like to draw your attention to my new article on genetic introgression from archaic humans, written with Gregory Cochran. The article is in PaleoAnthrop...

Neandertal genome FAQ

26 minute read

With the release of the initial two papers describing chromosomal DNA sequences from a Neandertal, I thought I would put together some frequently asked ques...

Why introgression?

2 minute read

I heard from a long-time correspondent this morning concerning introgression of microcephalin from archaic humans. I'm not sharing the whole message, but I ...

Neandertal genome project

3 minute read

By now you've probably read something about the Neandertal genome project. But have you seen the press kit from 454 Life Sciences?

Vindija nuclear DNA report

3 minute read

Nature News is reporting that a million base pairs of a Neandertal specimen from Vindija cave have been sequenced. There's no paper; it's just a press repor...

Has the dam broken on mtDNA selection?

4 minute read

The current Science has a paper by Eric Bazin and colleagues comparing mtDNA diversity with population size, history and ecology of 3000 animal species.

Mitochondrial disease minireview

2 minute read

This week's Nature had a news feature by Nick Lane about mitochondrial disease. I found it interesting because it focuses not only on disorders associated w...

An LDS DNA difficulty

3 minute read

The LA Times is carrying a story by writer William Lobdell about the apparent conflict between the Book of Mormon and DNA evidence for New World settlement....

Serial founder effects

13 minute read

This post is from 2005, and reflects my analysis at the time. The concepts here remain correct but the current state of evidence about human genetic variatio...

BROADLY CONSISTENT WATCH I

3 minute read

I'm starting a new tradition here, the "Broadly Consistent Watch." If you see that headline, you can be sure I'll be noting an abuse of the term "broadly co...

The mammoth tundra

5 minute read

Geophysicist Sergey Zimov had an essay in the May 6 edition of Science concerning the ecological pressures that may have changed the Arctic ecosystem at the...

Cave bear genomics

8 minute read

A new article on the epub area of Science, by James Noonan (Lawrence Berkeley National Laboratory) describes the recovery of nuclear DNA sequences from cave...

The Neandertal mtDNA story: 2004 edition

7 minute read

Note: I wrote this post in 2005. We have learned vastly more about Neandertal genetics since then. These two papers are important to the history of discoveri...