Neandertal ancestors of African populations
Earlier this year, Lu Chen and coworkers from Joshua Akey’s research group published an assessment of the amount of Neandertal ancestry in the genomes of pre...
Earlier this year, Lu Chen and coworkers from Joshua Akey’s research group published an assessment of the amount of Neandertal ancestry in the genomes of pre...
Alon Keinan and Andrew Clark have a short report in the current Science examining the effects of recent human population growth on the expected spectrum of h...
Daniel MacArthur and colleagues have an important paper in Science, titled “A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes” M...
Re: Neandertal gene variants in Yoruba:
This post is from 2012. The comparisons here were based on information that has changed over time, with it now clear that East Asian populations have a small...
Sometimes people wonder why human genetics projects should bother to involve anthropologists.
I’ve received several questions over the last few weeks about human genome-wide mutation rates. Some people are noticing heterogeneity in mutation rate estim...
Last spring I wrote about a study that used whole-genome comparisons between parents and offspring to estimate the rate of per-genome mutation in humans (“A ...
When I wrote earlier in the week about the 1000 Genomes Project results, I mentioned that a second paper was being published in Science. That paper, by Peter...
The first of the papers describing results from the 1000 Genomes project has been released today in Nature 1000Genomes:Nature:2010.
Last week, a paper looking for the genetic causes of Miller syndrome reported the whole genomes of four members of a single family: two siblings with the dis...
The 1000 Genomes Project is for people. Now, is it time for 10,000 vertebrate genomes? Erika Check Hayden reports on the idea in Nature news:
I couple of people have asked me about a new paper in PLoS Genetics by Graham Coop and colleagues, titled, “The role of geography in human adaptation.” The p...
A reader helpfully pointed me to a new paper in PNAS that looks at the sampling scheme of the 1000 Genomes Project from the point of view of SNP discovery. T...