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paleoanthropology, genetics and evolution

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  • The RNA game

    Sun, 2012-07-01 08:23 -- John Hawks

    It's hard to predict folding patterns of RNA in cells. As Hayley Dunning describes, RNA has been "gamified" to give scientists some help: "Toying with RNA".

    Players of the game EteRNA are given a real-world RNA shape and asked to manipulate a chain of nucleotides to fit that shape, by observing how different patterns of nucleotides form certain structures, like loops or tails. Then, every week, a few molecules are selected for synthesis in a lab at Stanford to see how closely they match the desired shape.

    The game itself, "EteRNA", is pretty cute. It took me a few tries to realize it's pronounced like the first six-sevenths of "eternal".

    I wish there were some way to gamify paleoanthropology. I mean, something more illuminating than just sticking Neandertals into World of Warcraft.

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Neandertals

For years, I've worked on their bones. Now I'm working on their genes. Read more about the science studying these ancient people.

Denisova

From a finger bone of an ancient human came the record of a completely unexpected population. My lab is working on the science of the Denisova genome.

Acceleration

The advent of agriculture caused natural selection to speed up greatly in humans. We're uncovering some of the ways that populations have rapidly changed during the last 10,000 years.

Malapa

Just outside Johannesburg, the Malapa site is producing some of the most exciting finds in human evolution. This site is the headquarters of the Malapa Soft Tissue Project.