| Title | Older males beget more mutations. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Hurles, M |
| Journal | Nat Genet |
| Volume | 44 |
| Issue | 11 |
| Pagination | 1174-6 |
| Date Published | 2012 Oct 29 |
| ISSN | 1546-1718 |
| Keywords | mutation, mutation rate, paternal age |
| Abstract | Three papers characterizing human germline mutation rates bolster evidence for a relatively low rate of base substitution in modern humans and highlight a central role for paternal age in determining rates of mutation. These studies represent the advent of a transformation in our understanding of mutation rates and processes, which may ultimately have public health implications. |
| DOI | 10.1038/ng.2448 |
| Alternate Journal | Nat. Genet. |
| Citation Key | Hurles:older:2012 |
| PubMed ID | 23104062 |
Older males beget more mutations.
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