|Title||Cognitive functioning in humans with mutations of the PAX6 gene.|
|Publication Type||Journal Article|
|Year of Publication||2004|
|Authors||Thompson, PJ, Mitchell, TN, Free, SL, Williamson, KA, Hanson, IM, van Heyningen, V, Moore, AT, Sisodiya, SM|
|Date Published||2004 Apr 13|
|Keywords||brain, brain function, cognition, development, evo-devo|
Fourteen patients with PAX6 gene mutations and previously identified MRI abnormalities were administered tests of cognitive functioning. No deficits were found. A subgroup with agenesis of the anterior commissure performed significantly more poorly on measures of working memory than those without this abnormality, suggesting the anterior commissure may play a role in cognitive processing in addition to an earlier identified role in sensory development and processing.
Cognitive functioning in humans with mutations of the PAX6 gene.
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